Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics
A. M. Zhang, T. J. J. de Winter, S. Wang, S. Flibotte, Y. B. Zhao, X. Hu, H. Li, D. F. Schaeffer, J. D. Johnson, J. L. Kopp
This study uses single-cell transcriptomics to show hyperinsulinemia affects pancreatic cancer development and immune microenvironment by altering immune cell pathways and reducing pre-cancerous lesions.
bioRxiv · Mar 10, 2021Cancer Biology