Author

Y. B. Zhao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:statistical model· 1

Frequent Co-Authors

X. Hu· 2 shared A. M. Zhang· 1 shared C. Ellis· 1 shared C. M. J. Chu· 1 shared D. A. Dionne· 1 shared D. F. Schaeffer· 1 shared E. Panzhinskiy· 1 shared F. C. Lynn· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

X. Hu

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Author profile →

2 papers

Recent·Most cited

Dynamic Ins2 gene activity defines β-cell maturity states

C. M. J. Chu, H. Modi, S. Skovso, C. Ellis, N. A. J. Krentz, Y. B. Zhao, H. Cen, N. Noursadeghi, E. Panzhinskiy, X. Hu, D. A. Dionne, Y. h. Xia, S. Xuan, M. O. Huising, T. J. Kieffer, , J. Johnson

This study shows that β-cell heterogeneity in insulin production is due to dynamic Ins2 gene activity states, with high activity linked to maturity and reduced viability.

bioRxiv · Jul 18, 2022Cell Biology

Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics

A. M. Zhang, T. J. J. de Winter, S. Wang, S. Flibotte, Y. B. Zhao, X. Hu, H. Li, D. F. Schaeffer, J. D. Johnson, J. L. Kopp

This study uses single-cell transcriptomics to show hyperinsulinemia affects pancreatic cancer development and immune microenvironment by altering immune cell pathways and reducing pre-cancerous lesions.

bioRxiv · Mar 10, 2021Cancer Biology