Cancer BiologybioRxiv
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics
A. M. Zhang, T. J. J. de Winter, S. Wang…·J. L. Kopp
This study uses single-cell transcriptomics to show hyperinsulinemia affects pancreatic cancer development and immune microenvironment by altering immune cell pathways and reducing pre-cancerous lesions.