Atg8-LC3 controls systemic nutrient surplus signaling from flies to humans.
A. Madan, K. P. Kelly, C. E. Sullivan, M. E. Poling, A. E. Brent, M. Alassaf, J. Dubrulle, A. Rajan
This study identifies Atg8-LC3's role in leptin secretion across species, linking autophagy proteins to nutrient surplus signaling and organismal resilience.
bioRxiv · May 31, 2023 · PreprintPhysiology