Author

A. Mahmoodi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

J. M. Mejia Oneto· 2 shared M. Zakharian· 2 shared N. A. Yee· 2 shared S. Srinivasan· 2 shared K. Wu· 1 shared M. Aleckovic· 1 shared M. Royzen· 1 shared T.-H. Nguyen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. M. Mejia Oneto

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2 papers

Recent·Most cited

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

S. Srinivasan, N. A. Yee, M. Zakharian, M. Aleckovic, A. Mahmoodi, T.-H. Nguyen, J. M. Mejia Oneto

This paper demonstrates SQ3370, a click chemistry-activated cancer therapeutic, is safe in humans and shows translatability across species with effective tumor activation and immune response.

bioRxiv · Mar 28, 2023 · PreprintPharmacology & Toxicology

SQ3370 Activates Cytotoxic Drug via Click Chemistry at Tumor and Elicits Sustained Responses in Injected & Non-injected Lesions

S. Srinivasan, N. A. Yee, K. Wu, M. Zakharian, A. Mahmoodi, M. Royzen, J. M. Mejia Oneto

SQ3370 activates a cytotoxic drug at tumors via click chemistry, improving survival and inducing systemic anti-tumor responses in mice with injected and non-injected lesions.

bioRxiv · Oct 13, 2020Bioengineering