Cryo-ET of a human GBP coatomer governing cell-autonomous innate immunity to infection
J. D. MacMicking, S. Zhu, C. J. Bradfield, A. Maminska, E. Park, B. Kim, P. Kumar, S. Huang, Y. Zhang, J. Bewersdorf
The paper solves the native structure of a human GBP coatomer that coats cytosolic bacteria and functions as an antimicrobial signaling platform.
bioRxiv · Aug 26, 2021 · PreprintImmunology