Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance.
C. Alcon, A. Manzano-Munoz, E. Prada, J. Mora, A. Soriano, G. Guillen, S. Gallego, J. Roma, J. Samitier, A. Villanueva, J. Montero
This study uses dynamic BH3 Profiling to identify BH3 mimetic combinations that enhance chemotherapy efficacy and prevent resistance in rhabdomyosarcoma.
bioRxiv · Jan 24, 2020Cancer Biology