Author

A. Mecate-Zambrano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. Brunotte· 2 shared S. Ludwig· 2 shared S. Schloer· 2 shared U. Rescher· 2 shared J. Goretzko· 1 shared J. TangiD· 1 shared N. Korthals· 1 shared S. Zheng· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

L. Brunotte

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologyEmerging Microbes & InfectionsPeer-reviewedOct 17, 2020

Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine

S. Schloer, L. Brunotte, J. Goretzko…·U. Rescher

This study identifies fluoxetine and other FIASMAs as inhibitors of SARS-CoV-2 entry by targeting endolysosomal acidification and cholesterol accumulation.

DOI 10.1080/22221751.2020.1829082

humanbulk RNA-seq

Pharmacology & ToxicologybioRxivOct 16, 2020

Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS-CoV-2 infection in vitro

U. Rescher, S. Schloer, L. Brunotte…·S. Ludwig

This study evaluates the antiviral effects of combining remdesivir with repurposed drugs fluoxetine and itraconazole, showing >90% inhibition of SARS-CoV-2 particle production in vitro.

DOI 10.1111/bph.15418

humanbulk RNA-seq