Author

A. Medvedev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Lin· 2 shared E. Martsen· 2 shared S. Makarov· 2 shared S. S. Makarov· 2 shared K. Gorman· 1 shared K. L. Gorman· 1 shared L. A. Medvedeva· 1 shared L. Medvedeva· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersPharmacology & Toxicology

B. Lin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Assessing risks and mechanisms of idiosyncratic drug toxicity by fingerprints of cell signaling responses.

A. Medvedev, S. Makarov, L. Medvedeva, E. Martsen, K. Gorman, B. Lin, S. S. Makarov

The paper assesses idiosyncratic drug toxicity by analyzing cell signaling responses, finding that drugs with smaller safety margins are more likely to cause liver injury.

bioRxiv · Dec 1, 2022 · PreprintPharmacology & Toxicology

Illuminating kinase inhibitors biology by cell signaling profiling.

A. Medvedev, S. Makarov, L. A. Medvedeva, E. Martsen, K. L. Gorman, B. Lin, S. S. Makarov

This paper introduces a method to evaluate kinase inhibitors by profiling transcription factor activity, revealing consensus signatures that indicate on-target biological effects.

bioRxiv · Apr 3, 2022 · PreprintPharmacology & Toxicology