Aspergillus fumigatus can display persistence to the fungicidal drug voriconazole
J. Scott, C. Valero, A. Mato-Lopez, I. J. Donaldson, A. Roldan, H. Chown, N. Van-Rhijn, R. Lobo-Vega, S. Gago, T. Furukawa, A. Morogovsky, R. Ben Ami, P. Bowyer, N. Osherov, T. Fontaine, , J. Amich
This study shows that some Aspergillus fumigatus isolates can persist in the presence of voriconazole, a fungicidal drug, and this persistence is associated with a distinct transcriptional profile and reduced treatment efficacy.
bioRxiv · May 16, 2022 · PreprintMicrobiology