Author

A. N. Brooks

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Genetic & Genomic Medicine· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:variant effect prediction· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

A. Banerjee· 1 shared A. Berger· 1 shared A. Clark-ElSayed· 1 shared A. E. Carpenter· 1 shared A. Kamath· 1 shared A. M. Thornton· 1 shared A. P. Wiita· 1 shared Alessandro BrusellesiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Banerjee

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder

Daniel Greene, Rodrigo Mendez, Jonathan Gill Lees, Mafalda Barbosa, Alessandro Bruselles, Luigi Chiriatti, Federico Ferraro, Cecilia Mancini, Rachel Schot, Frank Sleutels, Enrico Bertini, Devon E. Bonner, Arjan Bouman, A. N. Brooks, Thomas A. Cassini, , Ernest Turro

The paper identifies biallelic variants in RNU2-2 as a common cause of recessive neurodevelopmental disorders, showing higher prevalence than the dominant form in England.

Nature Genetics · Mar 30, 2026Peer-reviewedGenetic & Genomic Medicine

Deep mutational scanning of essential bacterial proteins can guide antibiotic development

L. Dewachter, A. N. Brooks, K. Noon, C. Cialek, A. Clark-ElSayed, T. Schalck, N. Krishnamurthy, W. Versees, W. Vranken, J. Michiels

This study uses deep mutational scanning on E. coli proteins to identify antimicrobial targets and guide drug development by analyzing mutation effects and resistance potential.

bioRxiv · May 23, 2022Microbiology

Cell Painting predicts impact of lung cancer variants

J. C. Caicedo, J. Arevalo, F. Piccioni, M.-A. Bray, C. L. Hartland, X. Wu, A. N. Brooks, A. Berger, J. S. Boehm, A. E. Carpenter, S. Singh

The paper uses Cell Painting to predict the functional impact of lung cancer variants by analyzing cell morphology at the single-cell level.

bioRxiv · Nov 18, 2021Cancer Biology

Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2

E. K. Robinson, P. Jagannatha, S. Covarrubias, M. Cattle, R. Safavi, R. Song, K. Viswanathan, R. Abu-Shumays, M. Jain, S. M. Cloonan, E. K. Wakeland, M. Akeson, A. N. Brooks, S. Carpenter

The paper identifies inflammation-induced alternative first exon usage in immune genes, revealing a novel iron-regulated Aim2 isoform with a 5′UTR iron-responsive element.

bioRxiv · Jul 6, 2020Immunology

The UCSC Xena platform for public and private cancer genomics data visualization and interpretation

M. Goldman, B. Craft, M. Hastie, K. Repecka, F. McDade, A. Kamath, A. Banerjee, Y. Luo, D. Rogers, A. N. Brooks, J. Zhu, D. Haussler

The paper describes the UCSC Xena platform, which enables secure visualization and analysis of both public and private cancer genomics data through web-based tools and hubs.

bioRxiv · Sep 26, 2019Cancer Biology

Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma

H. H.-L. Huang, I. D. Ferguson, A. M. Thornton, C. Y. T. Lam, Y.-H. T. Lin, P. Bastola, P. Choudhry, M. C. Mariano, M. D. Marcoulis, J. Malato, P. Phojanakong, T. G. Martin, J. L. Wolf, S. W. Wong, N. Shah, , A. P. Wiita

The paper shows proteasome inhibitors modulate splicing in multiple myeloma, revealing spliceosome inhibition as a therapeutic target.

bioRxiv · Feb 3, 2019Cancer Biology