E. K. Robinson

LincRNA-Cox2 regulates smoke-induced inflammation in murine macrophages

This study identifies lincRNA-Cox2 as a regulator of smoke-induced inflammation in murine macrophages, showing its role in modulating inflammatory gene expression and splicing.

Helicobacter chronic stage inflammation undergoes fluctuations that are altered in tlpA mutants

This study shows that H. pylori chronic inflammation fluctuates over time, and tlpA mutants alter these dynamics without affecting colonization levels in later stages.

LincRNA-Cox2 functions to regulate inflammation in alveolar macrophages during acute lung injury.

This study identifies lincRNA-Cox2 as a regulator of immune gene expression in alveolar macrophages during acute lung injury using RNA-seq and transgenic mice.

Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2

The paper identifies inflammation-induced alternative first exon usage in immune genes, revealing a novel iron-regulated Aim2 isoform with a 5′UTR iron-responsive element.

Generation and utilization of a HEK-293T murine GM-CSF expressing cell line

The paper generates a HEK-293T cell line expressing murine GM-CSF and shows it supports dendritic cell and alveolar macrophage differentiation as an alternative to commercial GM-CSF.

High throughput CRISPR screening identifies genes involved in macrophage viability and inflammatory pathways

The paper uses CRISPR screening to identify genes essential for macrophage viability and regulators of inflammatory pathways like NF-κB and TNF signaling.