Adenosine Reduces Sinoatrial Node Cell AP Firing Rate by uncoupling its Membrane and Calcium Clocks
A. N. Wirth, K. Tsutsui, V. A. Maltsev, E. G. Lakatta
This study shows adenosine reduces sinoatrial node cell AP firing rate by uncoupling membrane and calcium clocks through Gi and Gβγ signaling.
bioRxiv · Jun 20, 2022 · PreprintPhysiology