Author

A. Nash

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:mechanistic / dynamical model· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:fungi (other)· 1

Frequent Co-Authors

C. Harms· 2 shared D. Wright· 2 shared J. Klein-Seetharaman· 2 shared L. Kumar· 2 shared S. K. SARKAR· 2 shared J. Planas· 1 shared J. Rhodes· 1 shared S. Kamboj· 1 shared

Activity by Year

2016-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

C. Harms

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Quantification of allosteric communications in matrix metalloprotease-1 on alpha-synuclein aggregates and substrate-dependent virtual screening

S. Kamboj, C. Harms, D. Wright, A. Nash, L. Kumar, J. Klein-Seetharaman, S. K. SARKAR

This paper quantifies allosteric communications in MMP1 on alpha-synuclein aggregates using FRET and virtual screening, showing substrate-dependent changes in ligand-binding sites.

bioRxiv · Jan 11, 2021 · PreprintBiophysics

Allosteric communications between domains modulate activity of matrix metalloprotease-1

L. Kumar, A. Nash, C. Harms, J. Planas, D. Wright, J. Klein-Seetharaman, S. K. Sarkar

This paper identifies functionally relevant inter-domain dynamics in MMP1 on collagen fibrils, showing that open conformations correlate with activity and can be modulated by mutations and ligands.

bioRxiv · Jun 4, 2020Biophysics

Simulations of CYP51A from Aspergillus fumigatus in a model bilayer provide insights into triazole drug resistance

A. Nash, J. Rhodes

This study simulates CYP51A from Aspergillus fumigatus in a lipid bilayer to investigate azole drug resistance mechanisms.

bioRxiv · Nov 17, 2016Biochemistry