A priority code in presequences: mitochondrial targeting signals assign specific import characteristics to precursor proteins
S. Roedl, Y. Hoffman, F. Jung, A. Nutz, A. Egeler, M. Raeschle, Z. Storchova, T. Muehlhaus, J. M. Herrmann
The paper classifies mitochondrial presequences into seven groups and identifies group A presequences as enhancing import efficiency through a specific targeting mechanism involving TOMM34.
bioRxiv · Jun 27, 2024 · PreprintBiochemistry