Cholesterol Restriction Primes RIG-I Antiviral Responses Through a Noncanonical Type I IFN Pathway
T. Nishimura, T. Kouwaki, K. Takashima, A. Ochi, Y. S. Mtali, H. Oshiumi
This study shows that cholesterol restriction enhances RIG-I antiviral responses via a noncanonical type I IFN pathway, with implications for viral pandemic treatments.
bioRxiv · May 19, 2024 · PreprintImmunology