Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids
E. Valle-Encinas, N. Aleksieva, C. Velasco Martinez, M. Dawes, M. Zverev, M. Muller, A. Offergeld, M. J. Smalley, C. Hogan, S. J. Forbes, T. G. Bird, T. C. Dale
This study investigates the role of canonical Wnt signaling in BEC-to-hepatocyte conversion during liver injury and shows its impact on epithelial cell plasticity in hepatic organoids.
bioRxiv · Nov 9, 2020 · PreprintCell Biology