Author

T. G. Bird

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:mouse· 5 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. May· 3 shared A. Hedley· 2 shared C. Kiourtis· 2 shared C. Nixon· 2 shared F. Fercoq· 2 shared L. M. Carlin· 2 shared O. J. Sansom· 2 shared W. Clark· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

S. May

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multimodal decoding of human liver regeneration

K. P. Matchett, J. W. Wilson-Kanamori, J. R. Portman, A. Kapourani, F. Fercoq, S. May, J. B. Mackey, M. Brice, E. Zajdel, M. Beltran-Sierra, E. F. Sutherland, G. C. Wilson, S. J. Wallace, L. Kitto, N. T. Younger, , N. C. Henderson

This study uses single-nuclei RNA sequencing and spatial profiling to create a single-cell atlas of human liver regeneration, identifying a novel migratory hepatocyte subpopulation and demonstrating that wound closure precedes hepatocyte proliferation.

bioRxiv · Feb 24, 2023Cell Biology

Maturation, developmental site, and pathology dictate murine neutrophil function

J. B. G. Mackey, A. J. McFarlane, T. Jamieson, R. Jackstadt, X. L. Raffo-Iraolagoitia, J. Secklehner, X. Cortes-Lavaud, F. Fercoq, W. Clarke, A. Hedley, K. Gilroy, S. Lilla, J. Vuononvirta, G. J. Graham, K. De Filippo, , L. M. Carlin

This study identifies Ly6G expression levels as a marker for neutrophil maturation stages and shows spleen-derived neutrophils mature faster with distinct transcriptional profiles.

bioRxiv · Jul 21, 2021 · PreprintImmunology

Genetic manipulation using hepatocyte-targeting adeno-associated viral vectors has minimal off-target effects.

C. Kiourtis, A. Wilczynska, C. Nixon, W. Clark, S. May, T. G. Bird

This study investigates the short-term off-target effects of AAV8 vectors in mice, finding minimal physiological and transcriptomic impacts with no evidence of liver injury.

bioRxiv · Feb 19, 2021 · PreprintCell Biology

Absent expansion of pericentral hepatocytes and altered physiology in Axin2CreERT2 mice

S. May, M. Mueller, C. R. Livingstone, G. Skalka, C. Nixon, A. Hedley, R. Shaw, W. Clark, T. M. Drake, C. Kiourtis, A. S. Rocha, O. J. Sansom, T. G. Bird

This study re-evaluates lineage tracing in Axin2CreERT2 mice and reports absence of pericentral hepatocyte expansion and altered Wnt pathway physiology.

bioRxiv · Dec 9, 2020 · PreprintCell Biology

Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids

E. Valle-Encinas, N. Aleksieva, C. Velasco Martinez, M. Dawes, M. Zverev, M. Muller, A. Offergeld, M. J. Smalley, C. Hogan, S. J. Forbes, T. G. Bird, T. C. Dale

This study investigates the role of canonical Wnt signaling in BEC-to-hepatocyte conversion during liver injury and shows its impact on epithelial cell plasticity in hepatic organoids.

bioRxiv · Nov 9, 2020 · PreprintCell Biology