Author

A. P. Ikujuni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Assay:protein structure· 2 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

J. S. G. Slusky· 3 shared S. J. Budiardjo· 3 shared E. Firlar· 2 shared J. Kaelber· 2 shared A. Cordova· 1 shared A. L. Calkins· 1 shared D. Case· 1 shared J. J. Stevens· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersBiophysics

J. S. G. Slusky

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3 papers

Recent·Most cited

Detergent headgroups control TolC folding in vitro

A. P. Ikujuni, S. J. Budiardjo, J. S. G. Slusky

This study shows that detergent headgroup composition affects TolC folding in vitro, with nonionic detergents promoting functional trimer formation while zwitterionic detergents induce non-native folds.

bioRxiv · Apr 28, 2022Biophysics

Colicin E1 opens its hinge to plug TolC

S. J. Budiardjo, J. J. Stevens, A. L. Calkins, A. P. Ikujuni, V. K. Wimalasena, E. Firlar, D. Case, J. S. Biteen, J. Kaelber, J. S. G. Slusky

This paper reports the first structure of colicin E1 bound to TolC, showing how it opens its hinge to plug the channel and inhibit antibiotic efflux.

bioRxiv · Aug 24, 2021Biophysics

High yield preparation of outer-membrane protein efflux pumps by in vitro refolding is concentration dependent

S. J. Budiardjo, A. P. Ikujuni, E. Firlar, A. Cordova, J. Kaelber, J. S. G. Slusky

This study develops a concentration-dependent refolding protocol for outer-membrane efflux pump proteins, enabling high-yield preparation and structural analysis.

bioRxiv · Sep 14, 2020Biophysics