Author

A. Pierzynska-Mach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:fluorescence / live-cell microscopy· 3 Organism:human· 3 Research Focus:imputation· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Diaspro· 3 shared C. Czada· 2 shared C. Vogel· 2 shared E. Ferrando-May· 2 shared F. Kappes· 2 shared G. Tortarolo· 2 shared G. Vicidomini· 2 shared S. Zappone· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

A. Diaspro

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Author profile →

5 papers

Recent·Most cited

A Compact and Effective Photon-Resolved Image Scanning Microscope

G. Tortarolo, A. Zunino, S. Piazza, M. Donato, S. Zappone, A. Pierzynska-Mach, M. Castello, G. Vicidomini

This paper introduces a data-acquisition module for fluorescence LSM that enhances single-photon imaging capabilities, enabling super-resolution and multi-species imaging.

bioRxiv · Jul 28, 2023Biophysics

DEK oncoprotein participates in heterochromatin replication via SUMO-dependent nuclear bodies

A. Pierzynska-Mach, C. Czada, C. Vogel, E. Gwosch, X. Osswald, D. Bartoschek, A. Diaspro, F. Kappes, E. Ferrando-May

This study identifies DEK bodies involved in heterochromatin replication and links DEK to SUMO regulation, highlighting its role in chromatin integrity and cancer.

bioRxiv · Mar 9, 2023Cell Biology

Super-resolution microscopy reveals the nanoscale organization of the DEK protein cancer biomarker

A. Pierzynska-Mach, A. Diaspro, F. Cella Zanacchi

This study uses super-resolution microscopy to analyze DEK protein organization in breast cancer cells, showing cluster features correlate with cell type and chromatin state.

bioRxiv · Feb 28, 2023 · PreprintBiophysics

Cooled SPAD array detector for low light-dose fluorescence laser scanning microscopy

E. Slenders, E. Perego, M. Buttafava, G. Tortarolo, E. Conca, S. Zappone, A. Pierzynska-Mach, F. Villa, E. M. Petrini, A. Barberis, A. Tosi, G. Vicidomini

This paper introduces a cooled SPAD array detector that reduces dark-noise, improving signal-to-noise ratio and enabling lower laser power for live-cell imaging and artifact-free fluorescence fluctuation spectroscopy.

bioRxiv · Aug 3, 2021Biophysics

The oncoprotein DEK affects the outcome of PARP1/2 inhibition during replication stress

E. Ferrando-May, M. Ganz, C. Vogel, C. Czada, V. Jörke, R. Kleiner, A. Pierzynska-Mach, F. C. Zanacchi, A. Diaspro, F. Kappes, A. Bürkle

This study shows that DEK interacts with PAR to influence replication fork progression under stress, affecting PARP1/2 inhibitor efficacy in cancer cells.

bioRxiv · Feb 19, 2019Cancer Biology