Author

M. Castello

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biophysics· 3 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 6 Research Focus:imputation· 5 Approach:microscopy & imaging analysis· 4 Research Focus:dimensionality reduction· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

G. Tortarolo· 5 shared G. Vicidomini· 5 shared A. Diaspro· 4 shared P. Bianchini· 4 shared C. J. R. Sheppard· 3 shared A. Tosi· 2 shared A. Zunino· 2 shared F. Villa· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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5 shared papersBioengineering

G. Tortarolo

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Unveiling the Emotional Turmoil: How Covid-19 impacted researchers and the pursuit of emotional well-being in academia.

C. Weise, N. Sole-Suner, M. Corcelles, A. Sala-Bubare, M. Castello

This study examines the emotional impact of the Covid-19 lockdown on researchers, identifying factors like age, gender, and work-life balance that contribute to burnout and distress.

bioRxiv · Nov 15, 2023 · PreprintScientific Communication & Education

A Compact and Effective Photon-Resolved Image Scanning Microscope

G. Tortarolo, A. Zunino, S. Piazza, M. Donato, S. Zappone, A. Pierzynska-Mach, M. Castello, G. Vicidomini

This paper introduces a data-acquisition module for fluorescence LSM that enhances single-photon imaging capabilities, enabling super-resolution and multi-species imaging.

bioRxiv · Jul 28, 2023Biophysics

Nanoscale engagement and clusterization of Programmed death ligand 1 (PD-L1) in the membrane lipid rafts of Non-Small Cell Lung Cancer cells

M. Ruglioni, S. Civita, T. Salvadori, S. Cristiani, V. Carnicelli, S. Barachini, I. Petrini, I. Nepita, M. Castello, A. Diaspro, P. Bianchini, B. Storti, R. Bizzarri, S. Fogli, R. Danesi

This study uses super-resolution microscopy to show PD-L1 clusters in lipid rafts of NSCLC cells, suggesting new immuno-oncology targets.

bioRxiv · Aug 9, 2022 · PreprintBiophysics

Focus-ISM for Sharp and Gentle Super-Resolved Microscopy

G. Tortarolo, A. Zunino, F. Fersini, M. Castello, S. Piazza, C. J. R. Sheppard, P. Bianchini, A. Diaspro, S. Koho, G. Vicidomini

The paper introduces focus-ISM, a method combining STED and ISM to improve super-resolution microscopy for live and thick samples without compromising image quality.

bioRxiv · Apr 28, 2022Biophysics

Synergic Combination of Stimulated Emission Depletion Microscopy with Image Scanning Microscopy to Reduce Light Dosage

G. Tortarolo, M. Castello, S. V. Koho, G. Vicidomini

This paper combines STED microscopy with image scanning microscopy to reduce light dosage while maintaining resolution.

bioRxiv · Aug 21, 2019 · PreprintBioengineering

Easy Two-Photon Image Scanning Microscopy with SPAD Array and Blind Image Reconstruction

S. V. Koho, E. Slenders, G. Tortarolo, M. Castello, M. Buttafava, F. Villa, E. Tcarenkova, M. Ameloot, P. Bianchini, C. J. R. Sheppard, A. Diaspro, A. Tosi, G. Vicidomini

This paper introduces a two-photon image scanning microscopy (2PE-ISM) system that improves optical resolution and image quality without user calibration.

bioRxiv · Apr 27, 2019Bioengineering

Image Scanning Microscopy with Single-Photon Detector Array

M. Castello, G. Tortarolo, M. Buttafava, T. Deguchi, F. Villa, S. Koho, P. Bianchini, C. J. R. Sheppard, A. Diaspro, A. Tosi, G. Vicidomini

This paper introduces an improved image scanning microscopy technique using a single-photon detector array, enabling better resolution while maintaining compatibility with existing confocal microscopes and fluorescence spectroscopy methods.

bioRxiv · Jun 2, 2018Bioengineering