Author

A. Pons-Grifols

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

B. Trinite· 4 shared F. Tarres-Freixas· 4 shared J. Blanco· 4 shared A. Valencia· 3 shared B. Clotet· 3 shared E. Ballana· 3 shared E. Riveira-Munoz· 3 shared J. Carrillo· 3 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

B. Trinite

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

VLP-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice

A. Barajas, P. Amengual-Rigo, A. Pons-Grifols, R. Ortiz, O. Garcia Carmona, V. Urrea, N. de la Iglesia, J. Blanco-Heredia, C. Anjos-Souza, I. Varela, B. Trinite, F. Tarres-Freixas, C. Rovirosa, R. Lepore, M. Vazquez, , J. Blanco

This study develops a neoantigen selection pipeline and a VLP-based vaccine platform to enhance immunogenicity and antitumor activity in mice.

bioRxiv · Sep 7, 2023 · PreprintImmunology

Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant.

J. Carrillo, C. Avila-Nieto, J. Vergara-Alert, P. Amengual-Rigo, E. Ainsua-Enrich, M. Brustolin, M. L. Rodriguez de la Concepcion, N. Pedreno-Lopez, J. Rodon, V. Urrea, E. Pradenas, S. Marfil, E. Ballana, E. Riveira-Munoz, M. Perez, , J. Segales

This paper identifies mutations that improve the production and efficacy of SARS-CoV-2 Spike proteins, protecting animal models from the Beta variant.

bioRxiv · Jul 7, 2023Immunology

A Novel Monoclonal Antibody Targeting a Large Surface of the Receptor Binding Motif Shows Pan-neutralizing SARS-CoV-2 Activity Including BQ.1.1 Variant

L. de Campos-Mata, B. Trinite, A. Modrego, S. Tejedor Vaquero, E. Pradenas, N. Rodrigo Melero, D. Carlero, S. Marfil, A. Pons-Grifols, M. T. Bueno-Carrasco, C. Santiago, F. Tarres-Freixas, V. Urrea, N. Izquierdo, E. Riveira-Munoz, , G. Magri

This study characterizes a new monoclonal antibody, 17T2, that broadly neutralizes SARS-CoV-2 variants, including BQ.1.1, and shows in vivo prophylactic activity against Omicron BA.1.1.

bioRxiv · Jan 20, 2023 · PreprintImmunology

SARS-CoV-2 B.1.351 (beta) variant shows enhanced infectivity in K18-hACE2 transgenic mice and expanded tropism to wildtype mice compared to B.1 variant

F. Tarres-Freixas, B. Trinite, A. Pons-Grifols, M. Romero-Durana, E. Riveira-Munoz, C. Avila-Nieto, M. Perez, E. Garcia-Vidal, D. Perez-Zsolt, J. Munoz-Basagoiti, D. Raich-Regue, N. Izquierdo-Useros, I. Blanco, M. Noguera-Julian, V. Guallar, , J. Blanco

This study shows that the SARS-CoV-2 B.1.351 variant infects K18-hACE2 mice faster and wildtype mice, with milder symptoms than the B.1 variant.

bioRxiv · Aug 3, 2021 · PreprintMicrobiology