Author

C. Avila-Nieto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Valencia· 4 shared B. Clotet· 4 shared J. Blanco· 4 shared J. Carrillo· 4 shared J. Vergara-Alert· 4 shared N. Izquierdo-Useros· 4 shared V. Guallar· 4 shared B. Trinite· 3 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

A. Valencia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant.

J. Carrillo, C. Avila-Nieto, J. Vergara-Alert, P. Amengual-Rigo, E. Ainsua-Enrich, M. Brustolin, M. L. Rodriguez de la Concepcion, N. Pedreno-Lopez, J. Rodon, V. Urrea, E. Pradenas, S. Marfil, E. Ballana, E. Riveira-Munoz, M. Perez, , J. Segales

This paper identifies mutations that improve the production and efficacy of SARS-CoV-2 Spike proteins, protecting animal models from the Beta variant.

bioRxiv · Jul 7, 2023Immunology

SARS-CoV-2 B.1.351 (beta) variant shows enhanced infectivity in K18-hACE2 transgenic mice and expanded tropism to wildtype mice compared to B.1 variant

F. Tarres-Freixas, B. Trinite, A. Pons-Grifols, M. Romero-Durana, E. Riveira-Munoz, C. Avila-Nieto, M. Perez, E. Garcia-Vidal, D. Perez-Zsolt, J. Munoz-Basagoiti, D. Raich-Regue, N. Izquierdo-Useros, I. Blanco, M. Noguera-Julian, V. Guallar, , J. Blanco

This study shows that the SARS-CoV-2 B.1.351 variant infects K18-hACE2 mice faster and wildtype mice, with milder symptoms than the B.1 variant.

bioRxiv · Aug 3, 2021 · PreprintMicrobiology

Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in hamsters

M. Brustolin, J. Rodon, M. L. Rodriguez de la Concepcion, C. Avila-Nieto, G. Cantero, M. Perez, T. Nigeer, M. Noguera-Julian, V. Guallar, A. Valencia, N. Roca, N. Izquierdo-Useros, J. Blanco, B. Clotet, A. Bensaid, , J. Segales

This study shows that hamsters infected with SARS-CoV-2 are not fully protected against reinfection with both original and variant isolates, but experience reduced lung disease severity upon re-exposure.

bioRxiv · Jan 7, 2021 · PreprintPathology

Stable neutralizing antibody levels six months after mild and severe COVID-19 episode

E. Pradenas, B. Trinite, V. Urrea, S. Marfil, C. Avila-Nieto, M. L. Rodriguez de la Concepcion, F. Tarres-Freixas, S. Perez-Yanes, C. Rovirosa, E. Ainsua-Enrich, J. Rodon, J. Vergara-Alert, J. Sagales, V. Guallar, A. Valencia, , J. Blanco

This study tracks neutralizing antibody levels in COVID-19 patients up to six months post-infection, finding persistent activity in mild cases and a slower decline in hospitalized individuals.

bioRxiv · Nov 22, 2020Immunology