Author

N. Pedreno-Lopez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Organism:non-human primate· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

D. I. Watkins· 3 shared B. C. Rosen· 2 shared D. R. Burton· 2 shared E. G. Kallas· 2 shared L. M. S. Raphael· 2 shared L. M. Walker· 2 shared M. C. Bonaldo· 2 shared T. B. Voigt· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

D. I. Watkins

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant.

J. Carrillo, C. Avila-Nieto, J. Vergara-Alert, P. Amengual-Rigo, E. Ainsua-Enrich, M. Brustolin, M. L. Rodriguez de la Concepcion, N. Pedreno-Lopez, J. Rodon, V. Urrea, E. Pradenas, S. Marfil, E. Ballana, E. Riveira-Munoz, M. Perez, , J. Segales

This paper identifies mutations that improve the production and efficacy of SARS-CoV-2 Spike proteins, protecting animal models from the Beta variant.

bioRxiv · Jul 7, 2023Immunology

Therapeutic neutralizing monoclonal antibody administration protects against lethal viscerotropic Yellow Fever infection

M. J. Ricciardi, L. N. Rust, N. Pedreno-Lopez, S. Yusova, S. Biswas, G. M. Webb, M. Fischer, L. Gonsales-Nieto, T. B. Voigt, J. J. Louw, F. D. Laurino, J. R. DiBello, H.-P. Raue, L. M. S. Raphael, A. Yrizarry-Medina, , B. J. Burwitz

Therapeutic monoclonal antibodies prevent death from YFV infection.

bioRxiv · May 16, 2022 · PreprintImmunology

Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus

F. Zhao, Z. T. Berndsen, N. Pedreno-Lopez, A. Burns, J. D. Allen, S. Barman, W.-H. Lee, S. Chakraborty, S. Gnanakaran, L. M. Sewall, G. Ozorowski, O. Limbo, G. Song, P. Yong, S. Callaghan, , D. Sok

This study identifies nAbs against SIVmac239, reveals structural features of its Env trimer, and shows passive transfer of nAbs protects macaques from infection.

bioRxiv · Dec 22, 2021Immunology

Genotype-specific Features Reduce the Susceptibility of South American Yellow Fever Virus Strains to Vaccine-Induced Antibodies

D. Haslwanter, G. Lasso, A. Z. Wec, N. D. Furtado, L. M. S. Raphael, Y. Sun, S. Stransky, N. Pedreno-Lopez, A. Tse, C. A. Correia, Z. A. Bornholdt, M. Sakharkar, V. I. Avelino-Silva, C. L. Moyer, D. I. Watkins, , K. Chandran

This study shows that South American yellow fever virus strains are less susceptible to vaccine-induced antibodies due to genetic changes in the glycoprotein E.

bioRxiv · Aug 22, 2021Microbiology