Author

A. Poteete

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Biology Disciplines

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. P. Sulman· 1 shared F. M. Johnson· 1 shared F. Zhang· 1 shared J. Heymach· 1 shared J. P. Gudikote· 1 shared J. Wang· 1 shared J.-C. Bourdon· 1 shared L. Li· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

E. P. Sulman

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1 paper

Recent·Most cited

Inhibition of nonsense-mediated decay rescues functional p53β/γ isoforms in MDM2-amplified cancers

J. P. Gudikote, T. Cascone, A. Poteete, P. Sitthideatphaiboon, Q. Wu, N. Morikawa, F. Zhang, S. Peng, P. Tong, L. Li, L. Shen, M. Nilsson, P. Jones, E. P. Sulman, J. Wang, , J. Heymach

The paper shows that inhibiting nonsense-mediated decay increases expression of p53β/γ isoforms, which are resistant to MDM2 degradation, thereby restoring p53 function in cancers with MDM2 amplification, HPV infection, or specific p53 mutations.

bioRxiv · Apr 6, 2020 · PreprintCancer Biology