Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, A Potential Oral Drug Candidate for COVID-19 Treatment
A. Q. Wang, N. R. Hagen, E. C. Padilha, M. Yang, P. Shah, C. Z. Chen, W. Huang, P. Terse, P. Sanderson, W. Zheng, X. Xu
This study examines the preclinical pharmacokinetics and in vitro ADME properties of GS-441524, showing its stability across species and varying bioavailability, supporting its development as an oral drug candidate for COVID-19.
bioRxiv · Feb 7, 2022 · PreprintPharmacology & Toxicology