Author

A. R. Daamen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. C. Grammer· 2 shared P. E. Lipsky· 2 shared A. C. Labonte· 1 shared C. L. Mayberry· 1 shared C.-H. Chang· 1 shared D. C. Roopenian· 1 shared E. Bechtel· 1 shared E. L. Hubbard· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. C. Grammer

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Author profile →

3 papers

Recent·Most cited

Augmented glucose dependency of autoreactive B cells provides a treatment target forlupus

J. J. Wilson, J. Wei, A. R. Daamen, J. D. Sears, E. Bechtel, C. L. Mayberry, G. A. Stafford, L. Bechtold, A. C. Grammer, P. E. Lipsky, D. C. Roopenian, C.-H. Chang

This study identifies glycolysis-dependent autoreactive B cells as key mediators of lupus and shows that targeting them with 2DG or BCMA-specific CAR T-cells improves disease outcomes.

bioRxiv · Feb 1, 2022Immunology

c-Myb expression is critical to maintain proliferation and glucose metabolism of large pre-B cells

A. R. Daamen, R. B. Crittenden, T. P. Bender

This study shows c-Myb is essential for large pre-B cell proliferation, survival, and differentiation into small pre-B cells by regulating glucose metabolism and repressing Ikaros/Aiolos.

bioRxiv · Sep 9, 2020 · PreprintImmunology

Comprehensive Transcriptomic Analysis of COVID-19 Blood, Lung, and Airway

A. R. Daamen, P. Bachali, K. A. Owen, K. M. Kingsmore, E. L. Hubbard, A. C. Labonte, R. Robl, S. Shrotri, A. C. Grammer, P. E. Lipsky

This study analyzes gene expression in blood, lung, and airway tissues of COVID-19 patients to identify myeloid cell-driven inflammation and potential therapeutic targets.

bioRxiv · May 28, 2020Immunology