Author

A. R. Freitas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Organism:E. coli· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant calling· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. Novais· 4 shared L. Peixe· 4 shared T. M. Coque· 4 shared A. P. Pereira· 2 shared J. Corander· 2 shared P. Antunes· 2 shared R. J. L. Willems· 2 shared A. K. Pöntinen· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersMicrobiology

C. Novais

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Author profile →

4 papers

Recent·Most cited

The population-level impact of Enterococcus faecalis genetics on intestinal colonisation and extraintestinal infection

C. Chaguza, A. K. Pöntinen, J. Top, S. Arredondo-Alonso, A. R. Freitas, C. Novais, C. Torres, S. D. Bentley, L. Peixe, T. M. Coque, R. J. L. Willems, J. Corander

This study investigates the genetic factors influencing E. faecalis intestinal colonization and extraintestinal infection using GWAS and heritability analysis across 750 isolates.

bioRxiv · Sep 26, 2022 · PreprintMicrobiology

Evolution of chlorhexidine susceptibility and of the EfrEF operon among Enterococcus faecalis from diverse environments, clones and time spans

A. P. Pereira, P. Antunes, R. J. L. Willems, J. Corander, T. M. Coque, L. Peixe, A. R. Freitas, C. Novais

This study examines CHX susceptibility and ChlR-EfrEF variability in E. faecalis isolates from diverse environments, finding increased tolerance in food chain and recent human isolates.

bioRxiv · Jan 27, 2022Microbiology

Fitness cost of vancomycin-resistant Enterococcus faecium plasmids associated with hospital infection outbreaks

A. P. Tedim, V. F. Lanza, C. M. Rodriguez, A. R. Freitas, C. Novais, L. Peixe, F. Baquero, T. M. COQUE

The paper analyzes the fitness cost and stability of vancomycin-resistant plasmids in Enterococcus faecium and E. faecalis, showing reduced host fitness and plasmid stability under selective pressure.

bioRxiv · Jan 27, 2021Microbiology

Identification of 2CS-CHXT operon signature of chlorhexidine tolerance among Enterococcus faecium

B. Duarte, A. P. Pereira, A. R. Freitas, T. M. Coque, A. M. Hammerum, H. Hasman, P. Antunes, L. Peixe, C. Novais

This study identifies a 2CS-CHXT operon signature associated with chlorhexidine tolerance in Enterococcus faecium and proposes an epidemiological cut-off for detection.

bioRxiv · Jul 17, 2019Microbiology