L. Peixe

The population-level impact of Enterococcus faecalis genetics on intestinal colonisation and extraintestinal infection

This study investigates the genetic factors influencing E. faecalis intestinal colonization and extraintestinal infection using GWAS and heritability analysis across 750 isolates.

Evolution of chlorhexidine susceptibility and of the EfrEF operon among Enterococcus faecalis from diverse environments, clones and time spans

This study examines CHX susceptibility and ChlR-EfrEF variability in E. faecalis isolates from diverse environments, finding increased tolerance in food chain and recent human isolates.

Extended bacterial diversity of the urinary microbiome of reproductive-age healthy European women captured by culturomics and long-read amplicon sequencing

This study characterizes the urinary microbiome of healthy European women using culturomics and long-read sequencing, revealing high species diversity and inter-individual variation.

The darkest place is under the candlestick - healthy urogenital tract as a source of UTI-related Escherichia coli lineages

The paper investigates E. coli lineages in the healthy urogenital tract and finds they are closely related to UTI-causing strains, including antibiotic-resistant ST131.

Fitness cost of vancomycin-resistant Enterococcus faecium plasmids associated with hospital infection outbreaks

The paper analyzes the fitness cost and stability of vancomycin-resistant plasmids in Enterococcus faecium and E. faecalis, showing reduced host fitness and plasmid stability under selective pressure.

ICEs are the main reservoirs of the ciprofloxacin-modifying crpP gene in Pseudomonas aeruginosa

This study identifies ICEs as the main vectors for the dissemination of the ciprofloxacin-modifying crpP gene in Pseudomonas aeruginosa.

Identification of 2CS-CHXT operon signature of chlorhexidine tolerance among Enterococcus faecium

This study identifies a 2CS-CHXT operon signature associated with chlorhexidine tolerance in Enterococcus faecium and proposes an epidemiological cut-off for detection.

Megaplasmids on the rise: combining sequencing approaches to fully resolve a carbapenemase-encoding plasmid in a proposed novel Pseudomonas species

The paper combines Nanopore and Illumina sequencing to fully assemble a carbapenemase-encoding megaplasmid from a putative novel Pseudomonas species.

A large self-transmissible plasmid from Nigeria confers resistance to multiple antibacterials without a carrying cost

Carbapenemases on the move: it’s good to be on ICE

This study identifies ICEs in Pseudomonas aeruginosa that carry carbapenemase-encoding genes, highlighting their role in antibiotic resistance spread.