Single-cell transcriptomics reveals subset-specific metabolic profiles underpinning the bronchial epithelial response to flagellin
I. Ramirez-Moral, A. R. Schuurman, J. M. Butler, X. Yu, K. de Haan, S. van Leeuwen, A. D. de Vos, M. D. de Jong, F. A. Vieira Braga, T. van der Poll
The paper uses single-cell RNA sequencing to identify metabolic changes in bronchial epithelial cells responding to flagellin, showing inflammatory secretory cells undergo aerobic glycolysis.
bioRxiv · Nov 2, 2022Immunology