Author

A. Saris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

E. J. Nossent· 2 shared A. E. Oja· 1 shared A. H. Meijer· 1 shared A. R. Schuurman· 1 shared A. S. de Ries· 1 shared A. Ten Brinke· 1 shared B. M. Hogema· 1 shared C. A. Ghandour· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

E. J. Nossent

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria

R. H. G. A. van den Biggelaar, K. V. Walburg, S. van den Eeden, C. L. R. van Doorn, E. Meiler, A. S. de Ries, M. C. Fusco, A. H. Meijer, T. H. M. Ottenhoff, A. Saris

This study screens kinase inhibitors to identify host-directed therapies effective against intracellular bacteria Salmonella Typhimurium and Mycobacterium tuberculosis.

bioRxiv · Aug 28, 2023Microbiology

Distinct cellular immune profiles in the airways and blood of critically ill patients with COVID 19

A. Saris, T. D. Reijnders, E. J. Nossent, A. R. Schuurman, J. Verhoeff, S. D. van Asten, H. J. Bontkes, S. G. Blok, J. Duitman, H. J. Bogaard, L. Heunks, R. Lutter, T. van der Poll, J. J. Garcia Vallejo

This study compares immune profiles in airways and blood of severe COVID-19 patients, finding distinct T cell and inflammatory mediator patterns in bronchoalveolar lavage fluid versus plasma.

bioRxiv · Oct 29, 2020Immunology

Divergent SARS-CoV-2-specific T and B cell responses in severe but not mild COVID-19

A. E. Oja, A. Saris, C. A. Ghandour, N. A. M. Kragten, B. M. Hogema, E. J. Nossent, L. M. A. Heunks, S. Cuvalay, E. Slot, F. H. Swaneveld, H. Vrielink, T. Rispens, E. van der Schoot, R. A. W. van Lier, A. Ten Brinke, P. Hombrink

The paper compares T and B cell responses in severe versus mild COVID-19 patients, finding impaired CD4+ T cell responses but strong IgG antibodies in severe cases.

bioRxiv · Jun 18, 2020 · PreprintImmunology