Author

H. J. Bogaard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. Vidarsson· 2 shared H.-J. Chen· 2 shared J. Aman· 2 shared J. den Dunnen· 2 shared W. Hoepel· 2 shared A. Ainscough· 1 shared A. Neele· 1 shared A. P. Bye· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

G. Vidarsson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19

C. E. Geyer, H.-J. Chen, A. P. Bye, X. D. Manz, D. Guerra, T. G. Caniels, T. P. L. Bijl, G. R. Griffith, W. Hoepel, S. W. de Taeye, J. Veth, A. P. J. Vlaar, Amsterdam UMC COVID-19 Biobank, G. Vidarsson, H. J. Bogaard, , J. den Dunnen

The paper identifies SYK and PI3K inhibitors, particularly entospletinib, as effective in counteracting anti-spike IgG-induced hyperinflammation in severe COVID-19.

bioRxiv · Dec 20, 2022Immunology

Distinct cellular immune profiles in the airways and blood of critically ill patients with COVID 19

A. Saris, T. D. Reijnders, E. J. Nossent, A. R. Schuurman, J. Verhoeff, S. D. van Asten, H. J. Bontkes, S. G. Blok, J. Duitman, H. J. Bogaard, L. Heunks, R. Lutter, T. van der Poll, J. J. Garcia Vallejo

This study compares immune profiles in airways and blood of severe COVID-19 patients, finding distinct T cell and inflammatory mediator patterns in bronchoalveolar lavage fluid versus plasma.

bioRxiv · Oct 29, 2020Immunology

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

W. Hoepel, H.-J. Chen, S. Allahverdiyeva, X. Manz, J. Aman, P. Bonta, P. Brouwer, S. de Taeye, T. Caniels, K. van der Straten, K. Golebski, G. Griffith, R. Jonkers, M. Larsen, F. Linty, , J. den Dunnen

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients induces hyper-inflammatory responses in macrophages, leading to endothelial barrier breakdown and microvascular thrombosis.

bioRxiv · Jul 13, 2020Immunology

Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

H. Sindi, G. Russomanno, J. Kyeong Beom, V. B. Abdul-Salam, B. Q. Chaudhry, A. Ainscough, R. Szulcek, H. J. Bogaard, C. Morgan, S. S. Pullamsetti, M. Alzaydi, C. Rhodes, E. Grünig, C. Eichstaedt, M. R. Wilkins, B. Wojciak-Stothard

This study identifies KLF2-induced microRNAs that protect endothelial cells and reduce pulmonary hypertension in animal models and patient samples.

bioRxiv · Mar 21, 2019 · PreprintCell Biology