Targeted repression of DNA topoisomerase I by CRISPRi reveals a critical function for it in the Chlamydia trachomatis developmental cycle
L. Shen, L. Gao, A. R. Swoboda, S. P. Ouellette
This study uses CRISPRi to knock down topA in Chlamydia trachomatis, showing its critical role in developmental cycle and growth.
bioRxiv · Mar 14, 2023 · PreprintMicrobiology