Author

A. Rago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:contrastive learning· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. A. Watson· 2 shared T. Uller· 2 shared C. Banister· 1 shared C. Liu· 1 shared C. McTighe· 1 shared C. Thies· 1 shared I. Delgado· 1 shared J. H. Werren· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersEvolutionary Biology

R. A. Watson

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Author profile →

4 papers

Recent·Most cited

TP53 knockout in MCF7 breast cancer cells induces sensitivity to fluoropyrimidine drugs.

J. M. Warrington, S. Mehta, V. F. Moy, J. Patel, C. Liu, A. Rago, C. McTighe, I. Delgado, C. Banister, W. Gmeiner, P. J. Buckhaults

This study shows TP53 knockout in breast cancer cells increases sensitivity to fluoropyrimidine drugs like F10, with DNA incorporation as a key mechanism.

bioRxiv · Feb 10, 2022 · PreprintCancer Biology

Developmental models reveal the role of phenotypic plasticity in explaining genetic evolvability

M. Brun-Usan, A. Rago, C. Thies, T. Uller, R. A. Watson

The paper uses developmental models to show that phenotypic plasticity and genetic evolvability co-evolve, with plasticity providing faster adaptive gains.

bioRxiv · Jun 29, 2020 · PreprintEvolutionary Biology

Sex biased expression and co-expression networks in development, using the hymenopteran Nasonia vitripennis

A. Rago, J. H. Werren, J. K. Colbourne

The paper examines sex-biased gene expression and co-expression networks in Nasonia vitripennis across developmental stages, identifying sex determination candidates and network-specific regulatory genes.

bioRxiv · Feb 5, 2019Evolutionary Biology

How adaptive plasticity evolves when selected against

A. Rago, K. Kouvaris, T. Uller, R. A. Watson

This study shows adaptive plasticity can evolve in coarse-grained environments as a by-product of inefficient short-term selection, not through lineage or individual selection.

bioRxiv · Jun 5, 2018Evolutionary Biology