IDH-Tau-EGFR triad defines the neovascular landscape of diffuse gliomas by controlling mesenchymal differentiation
R. Gargini, B. Segura-Collar, V. Garcia-Escudero, A. Romero-Bravo, B. Herranz, F. J. Nunez, D. Garcia-Perez, A. Ayuso-Sacido, J. Seoane, J. M. Sepulveda-Sanchez, A. Hernandez-Lain, M. G. Castro, R. Garcia-Escudero, J. Avila, P. Sanchez-Gomez, , A. Perez-Nunez
This study identifies the IDH-Tau-EGFR triad as a key factor in defining the neovascular landscape of diffuse gliomas by regulating mesenchymal differentiation and vascular microenvironment.
bioRxiv · Oct 3, 2019Cancer Biology