MicrobiologybioRxiv
Generation and characterisation of P. falciparum parasites with a G358S mutation in the PfATP4 Na+ pump and clinically relevant levels of resistance to some PfATP4 inhibitors
D. Qiu, J. V. Pei, J. E. O. Rosling…·A. M. Lehane
This paper shows that a G358S mutation in PfATP4 confers clinically relevant resistance to cipargamin and (+)-SJ733 in P. falciparum parasites.
DOI 10.1038/s41467-022-33403-9