Author

A. Sachla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

J. D. Helmann· 3 shared A. Andreas· 1 shared A. Glasfeld· 1 shared B. He· 1 shared H. Shi· 1 shared H. Zhao· 1 shared K. Miller· 1 shared R. Shrestha· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

J. D. Helmann

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3 papers

Recent·Most cited

Structural basis for transcription activation through cooperative recruitment of MntR

H. Shi, Y. Fu, V. Kodyte, A. Andreas, A. Sachla, K. Miller, R. Shrestha, J. D. Helmann, A. Glasfeld, S. Ahuja

This study determines the structural basis of MntR-mediated gene activation through cooperative DNA binding using cryo-EM and complementary assays.

bioRxiv · Jun 28, 2024Biochemistry

TerC Proteins Function During Protein Secretion to Metalate Exoenzymes

B. He, A. Sachla, J. D. Helmann

The paper shows that TerC family proteins are involved in metalation of enzymes during secretion via the Sec pathway, specifically for manganese-dependent enzymes.

Nature Communications · Oct 4, 2023Peer-reviewedMicrobiology

Mutations of the YidC Insertase alleviate stress from σM-dependent membrane protein overproduction in Bacillus subtilis

H. Zhao, A. Sachla, J. D. Helmann

bioRxiv · Jun 20, 2019Microbiology