Author

A. Sadik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Gollowitzer· 1 shared A. Goncalves· 1 shared A. Kowar· 1 shared A. Leytens· 1 shared A. M. Heberle· 1 shared A. Marciniak-Czochra· 1 shared A. Martin-Villalba· 1 shared A. Reintjes· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Gollowitzer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression

L. C. Foerster, O. Kaya, V. Wust, D.-P. Danciu, M. Bekavac, K. C. Ziegler, V. Akcay, N. Stinchcombe, A. Tang, J. Tang, J. Brunken, N. Gesteira Perez, X. Ma, A. Sadik, C. Opitz, , A. Martin-Villalba

This study identifies SFRP1 as a therapeutic target for glioblastoma by revealing its role in reprogramming tumor methylomes and improving survival in mouse models.

bioRxiv · Sep 15, 2023Cancer Biology

The MTORC1-AHR pathway sustains translation and autophagy in tumours under tryptophan stress

P. Holfelder, L. Hensen, M. T. Prentzell, P. Razquin Navas, M. Solvay, A. Sadik, D. Sayeeram, U. Rehbein, T. Bausbacher, A.-S. Egger, L. Regin, A. M. Heberle, S. Seifert, A. Leytens, A. Kowar, , S. Harder

This study identifies the MTORC1-AHR pathway as a mechanism sustaining translation and autophagy in tumors under tryptophan stress by enhancing AHR activity and autophagy regulators.

bioRxiv · Jan 16, 2023 · PreprintBiochemistry