Author

E. S. Hong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. F. Bartels· 2 shared I. Bayles· 2 shared J. Lathia· 2 shared J. Lee· 2 shared J. Volovetz· 2 shared P. C. Scacheri· 2 shared S. Z. Wang· 2 shared W. D. Pontius· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

C. F. Bartels

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4 papers

Recent·Most cited

miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma

E. S. Hong, S. Z. Wang, A. K. Ponti, N. Hajdari, J. Lee, E. E. Mulkearns-Hubert, J. Volovetz, K. E. Kay, J. Lathia, A. Dhawan

This study identifies miR-644a as a tumor cell-intrinsic mediator of sex bias in glioblastoma, showing it is more highly expressed in females and its target genes are linked to poorer survival.

bioRxiv · Mar 11, 2024Cancer Biology

Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition

K. Kay, J. Lee, E. S. Hong, J. Beilis, S. Dayal, E. R. Wesley, S. Mitchell, S. Z. Wang, D. J. Silver, J. Volovetz, S. Johnson, M. McGraw, M. M. Grabowski, T. Lu, L. Freytag, , J. Lathia

This study shows that spermidine, a metabolite from glioblastoma cells, suppresses CD8+ T cell function, promoting tumor growth and poor patient outcomes.

bioRxiv · Nov 14, 2023Cancer Biology

Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis

W. D. Pontius, E. S. Hong, Z. J. Faber, J. Gray, C. Peacock, I. Bayles, K. Lovrenert, C. F. Bartels, P. C. Scacheri

This study identifies dynamic chromatin accessibility changes during osteosarcoma metastasis to the lung, revealing epigenetic states critical for metastatic colonization and new therapeutic targets.

Nature Communications · Nov 8, 2023Peer-reviewedCancer Biology

Mismatch-repair signature mutations activate gene enhancers across colorectal cancer epigenomes

S. Hung, A. Saiakhova, Z. Faber, C. F. Bartels, D. Neu, I. Bayles, E. Ojo, E. S. Hong, W. D. Pontius, A. R. Morton, R. Liu, M. F. Kalady, D. N. Wald, S. Markowitz, P. C. Scacheri

The paper identifies MMR signature mutations in colorectal cancer that activate enhancers by increasing FOX factor affinity and promoting tumor growth.

bioRxiv · Sep 7, 2018Cancer Biology