Irreversible temperature gating in trpv1 sheds light on channel activation
A. Sanchez-Moreno, E. Guevara-Hernandez, R. Contreras-Cervera, G. Rangel-Yescas, E. Ladron-de-Guevara, T. Rosenbaum, L. D. Islas
The paper identifies an irreversible inactivation process in TRPV1 channels triggered by thermal stimuli, linked to conformational changes in the membrane proximal domain.
bioRxiv · Jan 20, 2018Biophysics