BiophysicsbioRxiv
Irreversible temperature gating in trpv1 sheds light on channel activation
A. Sanchez-Moreno, E. Guevara-Hernandez, R. Contreras-Cervera…·L. D. Islas
The paper identifies an irreversible inactivation process in TRPV1 channels triggered by thermal stimuli, linked to conformational changes in the membrane proximal domain.
DOI 10.7554/elife.36372