Author

A. Sharrocks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

I. Ahmed· 2 shared S. Ogden· 2 shared The OCCAMS Consortium· 2 shared C. Francavilla· 1 shared P. Fullwood· 1 shared S.-H. Yang· 1 shared W. Zhang· 1 shared Y. Li· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

I. Ahmed

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2 papers

Recent·Most cited

Oncogenic ERRB2 signals through the AP-1 transcription factor to control mesenchymal-like properties of oesophageal adenocarcinoma

S. Ogden, I. Ahmed, P. Fullwood, The OCCAMS Consortium, C. Francavilla, A. Sharrocks

This study identifies AP-1 as a key transcription factor mediating ERBB2-driven mesenchymal-like properties in oesophageal adenocarcinoma through integrated phosphoproteomics, open chromatin profiling, and transcriptome analysis.

bioRxiv · Aug 14, 2022Cancer Biology

eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways

I. Ahmed, S.-H. Yang, S. Ogden, Y. Li, W. Zhang, the OCCAMs consortium, A. Sharrocks

The paper identifies enhancer RNAs in oesophageal adenocarcinoma using RNA-seq and open chromatin maps, revealing new deregulated pathways and their clinical relevance.

bioRxiv · May 11, 2022Cancer Biology