Author

G. Perkins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

G. C. Garcia· 2 shared K.-Y. Kim· 2 shared M. H. Ellisman· 2 shared S. Phan· 2 shared A. Mahapatra· 1 shared A. Skupin· 1 shared B. Roy· 1 shared C. Acree· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

G. C. Garcia

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Author profile →

4 papers

Recent·Most cited

Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.

C. d. Santos, S. Shrestha, M. A. Cottam, G. Perkins, V. Lev-Ram, B. Roy, C. Acree, K.-Y. Kim, T. Deerinck, M. Cutler, D. Dean, J. P. Cartailler, P. E. MacDonald, M. W. Hetzer, M. H. Ellisman, R. Arrojo e Drigo

This study shows caloric restriction enhances beta cell identity and homeostasis, delays aging and senescence, and improves mitochondrial function in pancreatic beta cells.

bioRxiv · Aug 23, 2023 · PreprintCell Biology

Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome

K. Venkatraman, C. T. Lee, G. C. Garcia, A. Mahapatra, D. Milshteyn, G. Perkins, K.-Y. Kim, H. A. Pasolli, S. Phan, J. Lippincott-Schwartz, M. Ellisman, P. Rangamani, I. Budin

The paper shows that cardiolipin buffers mitochondrial inner membrane curvature and ATP synthase organization, with a mathematical model predicting snapthrough instability in cristae formation.

bioRxiv · Mar 13, 2023 · PreprintBiophysics

Mitochondrial morphology provides a mechanism for energy buffering at synapses

G. C. Garcia, T. M. Bartol, S. Phan, E. A. Bushong, G. Perkins, T. J. Sejnowski, M. H. Ellisman, A. Skupin

The paper presents an agent-based model of mitochondrial morphology at synapses, showing that internal structure influences energy buffering and cellular robustness.

bioRxiv · May 20, 2019Biophysics

Proteomic profiling of the oncogenic septin 9 reveals isoform-specific interactions in breast cancer cells

L. Devlin, G. Perkins, J. R. Bowen, C. Montagna, E. T. Spiliotis

The paper identifies isoform-specific interactions of SEPT9 in breast cancer cells through proteomic analysis, revealing distinct molecular networks and functions for different SEPT9 variants.

bioRxiv · Mar 5, 2019Cell Biology