Drug-induced colorectal cancer persister cells show increased mutation rate
M. Russo, S. Pompei, A. Sogari, M. Corigliano, G. Crisafulli, A. Bertotti, M. Gherardi, F. Di Nicolantonio, A. Bardelli, M. C. Lagomarsino
The paper shows that drug treatment induces colorectal cancer persister cells with significantly increased mutation rates, suggesting new strategies to prevent tumor recurrence.
bioRxiv · May 17, 2021 · PreprintCancer Biology