Neurotrophin signaling is modulated by specific transmembrane domain interactions
M. L. Franco, K. D. Nadezhdin, T. P. Light, S. A. Goncharuk, A. Soler-Lopez, F. Ahmed, K. S. Mineev, K. Hristova, A. S. Arseniev, M. Vilar
The paper identifies and characterizes the direct interaction between TrkA and p75 through their transmembrane domains, showing its role in TrkA activation and cell differentiation.
bioRxiv · May 24, 2021 · PreprintBiochemistry