Author

T. P. Light

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

K. Hristova· 2 shared A. S. Arseniev· 1 shared A. Soler-Lopez· 1 shared B. C. Lechtenberg· 1 shared E. B. Pasquale· 1 shared F. Ahmed· 1 shared K. D. Nadezhdin· 1 shared K. S. Mineev· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

K. Hristova

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Neurotrophin signaling is modulated by specific transmembrane domain interactions

M. L. Franco, K. D. Nadezhdin, T. P. Light, S. A. Goncharuk, A. Soler-Lopez, F. Ahmed, K. S. Mineev, K. Hristova, A. S. Arseniev, M. Vilar

The paper identifies and characterizes the direct interaction between TrkA and p75 through their transmembrane domains, showing its role in TrkA activation and cell differentiation.

bioRxiv · May 24, 2021 · PreprintBiochemistry

Allosteric Regulation of the EphA2 Receptor Intracellular Region by Serine/Threonine Kinases

B. C. Lechtenberg, M. P. Gehring, T. P. Light, M. W. Matsumoto, K. Hristova, E. B. Pasquale

This study reveals two allosteric mechanisms by which serine/threonine phosphorylation of the EphA2 linker regulates its non-canonical signaling, providing insights into its role in cancer.

bioRxiv · Jan 28, 2021Biophysics