Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output
A. T. Lessenger, M. P. Swaffer, J. M. Skotheim, J. L. Feldman
The paper shows that polyploidy in C. elegans intestine increases transcriptional output and supports biosynthesis by compensating for mRNA dilution through increased RNA Polymerase II loading.
bioRxiv · Mar 25, 2024 · PreprintCell Biology