Author

A. Toor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:clinical cohort / trial· 1 Research Focus:clustering· 1

Frequent Co-Authors

J. Reed· 2 shared A Scalora· 1 shared A. Chesney· 1 shared A. Fowler· 1 shared A. Keating· 1 shared B Abdul Razzaq· 1 shared B. Fisher· 1 shared C Hall· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

J. Reed

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation

R. M. Bragg, S. R. Coffey, J. P. Cantle, S. Hu, S. Singh, S. R. W. Legg, C. A. McHugh, A. Toor, S. O. Zeitlin, S. Kwak, D. Howland, T. F. Vogt, S. P. Monga, J. B. Carroll

This study shows that reducing huntingtin in liver cells leads to metabolic changes, altered cell adhesion, and disrupted liver zonation patterns in mice.

bioRxiv · Jun 24, 2023 · PreprintCell Biology

Killer Immunoglobulin-like Receptor-Ligand Interactions Predict Clinical Outcomes Following Unrelated Donor Transplants

E. O. Krieger, R. Sabo, S. Moezzi, C. Cain, C. Roberst, P. Kimball, A. Chesney, J. McCarty, A. Keating, R. Romee, C. Wiedl, R. Qayyum, A. Toor

The paper develops a mathematical model to quantify KIR-KIRL interactions and shows that these interactions predict clinical outcomes in HLA-matched unrelated donor transplants.

bioRxiv · Jun 23, 2019Cancer Biology

Reduced Plasma Ascorbic Acid Levels in Recipients of Myeloablative Conditioning & Hematopoietic Cell Transplantation

M. Rasheed, G. Simmons, B. Fisher, K. Leslie, J. Reed, C. Roberts, R. Natarajan, A. Fowler, A. Toor

This study measures ascorbic acid levels in HCT patients post-MAC and finds reduced levels persisting longer in allogeneic recipients.

bioRxiv · Feb 3, 2019Physiology

T Cell Repertoire Evolution After Allogeneic Bone Marrow Transplantation: An Organizational Perspective

J. Meier, M. Fawaz, H. Abdeen, J. Reed, C. Kanakry, L. Luznik, A. Toor

This study quantifies T cell repertoire reconstitution after bone marrow transplantation by analyzing TCR β sequence organization, finding reduced repertoire complexity post-transplant and preserved VJ segment symmetry.

bioRxiv · May 21, 2018Immunology

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness in Clinical Outcomes Following Stem Cell Transplantation

V Koparde, B Abdul Razzaq, T Suntum, R Sabo, A Scalora, M Serrano, M Jameson-Lee, C Hall, D Kobulnicky, N Sheth, J Sampson, J Reed, C Roberts, R Qayyum, G Buck, , A. Toor

The paper models donor T cell responses to recipient peptides from whole exome sequencing to explore variability in GVHD outcomes after stem cell transplantation.

bioRxiv · Apr 6, 2017 · PreprintImmunology