Author

A. V. Shindyapina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Tyshkovskiy· 2 shared C. Kerepesi· 2 shared V. N. Gladyshev· 2 shared A. A. Indzhykulian· 1 shared A. Barbieri· 1 shared A. Bareja· 1 shared A. Karamyshev· 1 shared A. P. Petrashen· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

A. Tyshkovskiy

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2 papers

Recent·Most cited

Cell BiologybioRxivNov 11, 2021

Multi-omic rejuvenation and lifespan extension upon exposure to youthful circulation

B. Zhang, D. E. Lee, A. Trapp…·J. P. White

This study shows that prolonged heterochronic parabiosis reduces biological age and extends lifespan in mice through long-term epigenetic and transcriptomic changes.

DOI 10.1038/s43587-023-00451-9

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 23, 2021

Integrative analyses uncover mechanisms by which aging drives B cell lymphoma

J. P. Castro, A. V. Shindyapina, A. Barbieri…·V. N. Gladyshev

This study identifies age-associated clonal B cells (ACBCs) as drivers of B-cell lymphoma in mice, linking aging-related epigenetic and cellular changes to cancer development and proposing mTOR/c-Myc inhibition as a therapeutic strategy.

DOI 10.1101/2021.02.23.432500

mouseDNA methylation

𝕏 PostBluesky