Author

A. Vlahou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

M. Makridakis· 2 shared A. Boumpas· 1 shared A. Chatzigeorgiou· 1 shared A. Galaras· 1 shared A. Hatzioannou· 1 shared A. S. Papaioannou· 1 shared A. Tasis· 1 shared B. Malissen· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

M. Makridakis

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2 papers

Recent·Most cited

PD-L1 blockade immunotherapy rewires cancer emergency myelopoiesis

A. Boumpas, A. S. Papaioannou, P. Bousounis, M. Grigoriou, V. Bergo, I. Papafragkos, A. Tasis, M. Iskas, L. Boon, M. Makridakis, A. Vlahou, E. Gavriilaki, A. Hatzioannou, I. Mitroulis, E. Trompouki, P. Verginis

This study shows PD-L1 blockade in tumor-bearing mice targets bone marrow HSPCs, reprograms their transcriptome toward inflammation, and reduces myeloid-derived suppressor cells.

bioRxiv · Dec 20, 2023 · PreprintImmunology

Interferon-induced lysosomal membrane permeabilization and death cause cDC1-deserts in tumors.

E. Aerakis, A. Chatzigeorgiou, M.-M. Alvanou, M. Matthaiakaki-Panagiotaki, I. Angelidis, D. Koumadorakis, A. Galaras, P. Hatzis, D. Kerdidani, M. Makridakis, A. Vlahou, B. Malissen, S. Henri, M. Merad, M. Tsoumakidou

This study identifies interferon-induced lysosomal membrane permeabilization and death as mechanisms causing cDC1 scarcity in tumors, suggesting therapeutic strategies to enhance anti-tumor immunity.

bioRxiv · Mar 14, 2022 · PreprintImmunology